For Validation Partners

Clinical regimen in the field.

4 regimens, 1 protocol. Preventing exposure-linked brain diseases today, and cancers tomorrow. Proven over a decade in Ghana, now entering external validity through the FARMERBRAIN Global Study.
  • FH001-Diagnose™
  • FH002-Treat™
  • FH003-Monitor™
  • FH004-Sustain™
  • FH004-Sustain™
0 +
Neurological diseases and cancers
0 %
Protocol adherence
0
Years of evidence
  • Pipeline

Pipeline overview

FH001

Diagnose

FH002

Treat

FH003

Monitor

FH004

Sustain

Protocol Design
Clinical Feasibility
Clinical Deployment*
Global Validation
Africa
N. America
Asia
  • How the Clinical Loop Works

Four regimens form a single treatment cycle with insights.

01
FH001-Diagnose™
Diagnose
Health Guides screen for 30+ neurological diseases and cancers across exposure types.
02
FH002-Treat™
Treat
Health Guides distribute science-based PPEs to at-risk workers and refer some to clinics.
03
FH003-Monitor™
Monitor
Cholinesterase fingerstick system confirms protection is working. Tracked against baseline.
04
FH004-Sustain™
Sustain
Parents complete loop, kids get rewards. Adherent parents earn from surveys to pay Health Guides. Cycle repeats.
  • FH001-Diagnose™

Occupational Neurology Diagnostic

Indication

Screening for 30+ exposure-linked brain diseases and cancers

Mechanism of Action

Routes by exposure type, not presenting symptoms

Dosage Form
Four screening tools: pesticides, metals, heat, physical labor
Eligibility

Farm workers and their kids. Age 0–65+.

Conditions Screened (Partial List)

Parkinson's

Alzheimer's

ALS

Peripheral neuropathy

Reduced IQ

ADHD

Radiculopathy

Seizures

Leukemia

Non-Hodgkin lymphoma

Brain cancer

  • FH002-Treat™

Exposure Reduction Intervention

Indication

Reduce neurotoxic exposure in high-risk individuals

Mechanism of Action
Dermal, respiratory and ocular barrier protection
Dosage Form
Nitrile gloves, particulate-filtered mask, chemical splash goggles
Eligibility

Farming adults 16+ with active high-exposure flags

  • FH003-Monitor™

Treatment Response Assay

Indication
Confirms FH002-Treat™ intervention is working
Mechanism of Action
Cholinesterase activity measurement (ChE)
Dosage Form
4-minute fingerstick blood test. Tracked against baseline.
Eligibility
Farm workers and their children. Age 5+.

Clinical Interpretation Domains

OP/carbamate exposure

Nutritional status

Hepatic function

Renal function

Outcomes

98% adherence

100% community-funded Health Guides

  • FH004-Sustain™

Adherence-Driven Financing Regimen

Indication

Prevents cortisol-induced neuroinflammation. Maintains protocol adherence.

Mechanism of Action
Kids are rewarded when parents complete a loop. Parents take paid surveys.
Dosage Form

School supplies for kids. Cash earnings for parents.

Eligibility
Farm workers and their children. Age 5+.

A decade of extending the healthy lifespan of farming families.

  • Before
  • After
  • The FARMERBRAIN Global Study

The largest farmers' health trial in clinical medicine.

Tracking regimen effectiveness across real-world farming communities to support global deployment.

See The Science
West Africa
Ghana's Cocoa Belt
8 communities · 152 schools · Cocoa, cassava, palm oil exposure profiles · 10-year longitudinal outcomes on file
Enrollment: active
U.S. Northeast
Connecticut River Valley
17,600 farmworker families · 17 sites · Tobacco, orchard, nursery exposure profiles
Pending Partner: Agreements
Future
Additional study sites
Central & Latin America · Asia · Caribbean

Location Partners: Submit Interest

These farming-related diseases killed my family. They nearly killed me, too. And for 10 years, I've seen them steal kids' brains. Enough.

Dr. Shadrack Frimpong
Founder and Chief Clinical Officer, FarmerHealth by Cocoa360